Particle-based systems

Services

NANOCYTES® / Core-shell particles

  • Development and synthesis of highly specific adsorber polymers
  • Development of NANOCYTES® surfaces for DNA- and protein microarrays
  • Surface coating of micro- and nanoparticles
  • Design and production of selective composite membranes
  • Organic and inorganic particle-based systems
  • Formulation of drug matrix systems
  • Development of biocompatible and biodegradable particles
  • Loading and encapsulating of particles
  • Production of nanoparticles with reactive active ester surface
  • Bioconjugation of biomolecules on surfaces
  • Biological analyses and analytics
  • Carrying out feasibility studies

Development of nano- and micro-encapsulated active agents

  • Synthesis of polymers and block co-polymers
  • Characterization of polymers
  • Bioconjugation

Drug loading of particles

  • Formulation of particles via mini- and nano-spray dryer
  • High performance liquid chromatography (HPLC)
  • Titration microcalorimetry
  • Characterization of carbon-based nanomaterials at nearly all stages of a process with regard to:
  • Structure/morphology
  • Atomic composition
  • Conductivity
  • Functionalization
  • Wettability
  • Grafting properties
  • Toxicity/biocompatibility
  • Particle characterization

Printing processes

  • Formulation of water- or solvent-based inkjet inks
  • Biofunctional inks
  • Inks containing nano- or microparticles
  • UV-crosslinkable inks
  • Conductive and printed circuit board inks
  • Printing of high-resolution structures

Carbon-based nanomaterials

  • Manufacturing of bucky paper and CNT-based membranes
  • Development of CNT polymer composites
  • Functionalization or coating of such materials by means of plasma technology, wet chemistry, or grafting techniques for
  • Modified wettability/solubility
  • Polymer composite development
  • Testing of toxicity and biocompatibility using our cell test systems

Equipment

Biological and polymer analytics

  • MALDI-TOF/TOF mass spectrometer (Bruker Ultraflex II)
  • Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)
  • Simultaneous thermoanalysis (STA)
  • Gel permeation chromatography (GPC) with 4 detectors

Particle analysis

  • Microelectrophoresis (zeta potential)
  • Dynamic light scattering (SLS, mastersizer, measuring range 0.1 nm to 10 μm)
  • Static light scattering (SLS, mastersizer, measuring range 50 nm to 2 mm)
  • Miniplants with inline analytics

Surface characteristics and morphology

  • Ellipsometry
  • Microscopy, scanning electron microscope (REM), atomic force microscopy (AFM)
  • Electron spectroscopy for chemical analysis (ESCA)
  • Mini- and nano-spray dryer for the formulation of particles
  • High performance liquid chromatography (HPLC)
  • Titration microcalorimetry

Formulations

  • Dynamic light scattering
  • Ellipsometry
  • MALDI TOF mass spectrometry
  • Microcalorimetry
  • Digital imaging
  • Laboratory synthesis

Carbon-based materials