At the Fraunhofer IGB we use well-established chemical and physical crosslinking technologies to produce tissue-like hydrogels. Additionally, in our laboratories we develop our own processes and biocompatible crosslinkers that are suitable, for example, for in situ encapsulation of cells or that simulate special properties such as the elasticity of natural tissues.
We work with photo-induced, radical crosslinking and initiator-free reactions on the basis of click chemistry. Using physical crosslinkings triggered by pH or temperature changes, we can produce customized reversible switchable networks.
The controlled crosslinking of synthetic or bio-based molecular building blocks results in hydrogels with adjustable mechanical and biological properties.