Fraunhofer IGB is working successfully in numerous (joint) projects funded by German Federal Ministries or by foundations. Here we present a selection of current and completed projects.
Funding: BMBF || Duration: October 2014 – March 2018 || In the joint project Auto-loop, a new principle for the tissue-specific release of drugs will be developed using the example of inflammatory diseases. It is based on the fact that a drug will only be released at its target site when proteases correlated with the disease are present in a sufficiently high concentration and release the drug bound via a peptide chain from its carrier polymer. The cleavage sites for the respective proteases are defined by indication-specific linkers introduced using click chemistry.more info