Medical Biotechnology

We develop technologies for preventive and precision medicine in close cooperation with clinics and industry. Our focus is on virus-based therapeutics and diagnostics.

In the field of In-vitro Diagnostics, we are working on new liquid biopsy methods for indications with high medical need, such as early cancer detection, with a focus on prevention and precision. Our expertise covers the entire chain from sample collection to medical reporting. Core technologies include sample preparation, next-generation sequencing (NGS), and bioinformatic analysis using machine learning and artificial intelligence. This enables us to identify characteristic biomarker patterns that, for example, enable improved early detection of tumors or rapid identification of microbial pathogens in sepsis and complex infectious diseases.

In the field of Virus-Based Technologies and Therapies, we focus on the development of process technologies (CMC – chemistry, manufacturing, and controls) for the efficient production of therapeutic viruses (oncolytic viruses, vaccine vectors). These are based on three pillars: cellular production technologies (upstream), purification processes for active viruses (downstream) and their formulations, and analytical methods for qualifying virus products. This includes the integration of omics technologies for precision process development. Our approach enables us to form a competence hub for CMC screening of virus-based technologies – neutral, manufacturer-independent, industry-oriented, and scientifically sound. For all relevant CMC modules, we develop a clear assessment of GMP compatibility, scale-up capability, delivery reliability, and cost structure.