Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB

Kubik, Grzegorz Dr.

Head of the Industrial Biotechnology Innovation Field

Dr. Grzegorz (Greg) Kubik has made it his mission to transform the chemical industry into a more environment-friendly one by implementating biotechnological methods. He is a trained chemist with more than 10 years of interdisciplinary experience in the field of biotechnology in various international positions as a scientist, project manager and business development manager both in science and industry. Since July 2021 he is the head of the Innovation Field Industrial Biotechnology at Fraunhofer IGB.

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  • Professional career
    Since 07/2021 Head of Innovation Field Industrial Biotechnology at Fraunhofer IGB
    07/2020 – 06/2021  Senior Manager Business Development with Synbionik GmbH
    01/2019 – 07/2020  Business Development Manager with Enzymaster Deutschland GmbH
    06/2016 – 05/2018  Postdoctoral Researcher at Caltech with Frances H. Arnold
    10/2012 – 01/2016  PhD in Chemistry at University of Konstanz and Konstanz Research School Chemical Biology
    10/2007 – 07/2012 Studies in Chemistry at RWTH Aachen University with specialization in organic chemistry, catalysis and industrial chemistry

  • [12]  Giess M., Munoz-Lopez A., Buchmuller B., Kubik G., Summerer D., „Programmable Protein-DNA Crosslinking for the Direct Capture and Quantification of 5-Formylcytosine”, J. Am. Chem. Soc. 2019, 141 (24), 9453-9547. 

    [11] Hammer S.C., Kubik G., Watkins E.J., Minges H., Huang S., Arnold F.H., „Anti-Markovnikov alkene oxidation by metal-oxo-mediated enzyme catalysis”, Science 2017, 358, 215-218. (Highlighted in “Research of the Year”, C&EN 2017, 95 (49), 19 and Synfacts 2018, 14 (1), 83.)

    [10]  Flade S., Jasper J., Giess M., Juhasz M., Dankers A., Kubik G., Koch O., Weinhold E., Summerer D., „The N6-Position of Adenine is a Blind Spot for TAL-Effectors that Enables Effective Binding of Methylated and Fluorophore-Labeled DNA”, ACS Chem. Biol. 2017, 12 (7), 1719–1725.

     [9]  Rathi P., Maurer S., Kubik G., Summerer D., „Isolation of Human Genomic DNA Sequences with Expanded Nucleobase Selectivity”, J. Am. Chem. Soc. 2016, 138 (31), 9910–9918.

    [8]   Kubik G., Summerer D., „TALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis”, ChemBioChem 2016, 17 (11), 975-980.

    [7]   Kubik G., Summerer D., „Deciphering Epigenetic Cytosine Modifications by Direct Molecular Recognition”, ACS Chem. Biol. 2015, 10, 1580-1589.

    [6]   Kubik G., Batke S., Summerer D., „Programmable Sensors of 5‑Hydroxymethylcytosine”, J. Am. Chem. Soc. 2015, 137 (1), 2-5.

    [5]   Kubik G., Summerer D., „Achieving single nucleotide resolution of 5‑methylcytosine detection with TALEs”, ChemBioChem 2015, 16 (2), 228-231.

    [4]   Kubik G., Schmidt M.J., Penner J.E., Summerer D., „Programmable and Highly Resolved in vitro Detection of 5-Methylcytosine by TALEs“, Angew. Chem. Int. Ed. 2014, 23, 6002-6006.

    [3]   Haven T., Kubik G., Haubenreisser S., Niggemann M., „Calcium Catalyzed Cyclopropanation”, Angew. Chem. Int. Ed. 2013, 14, 4016-4019. (Highlighted in Synfacts 2013, 9 (6), 619.)

    [2]   Ma G., Lin S., Ibrahem I., Kubik G., Liu L., Sun J., Córdova A., „Achiral Co-Catalyst Induced Switches in Catalytic Asymmetric Reactions on Racemic Mixtures (RRM): From Stereodivergent RRM to Stereoconvergent Deracemization by Combination of Hydrogen Bond Donating and Chiral Amine Catalysts”, Adv. Synth. Catal. 2012, 14-15, 2865–2872.

    [1]   Giese M., Albrecht M., Wiemer K., Kubik G., Valkonen A., Rissanen K., „Weak Intermolecular Anion–π Interactions in Pentafluorobenzyl-Substituted Ammonium Betaines“, Eur. J. Inorg. Chem. 2012, 18, 2995–2999.

    Patents

    [3]   Hu Hu (胡虎), Marco Bocola (马克·博科拉), Grzegorz Kubik (格雷戈日·库比克), Chen Haibin (陈海滨), Jin Ou Ping (金炉萍), “Method for synthesizing R-3-(2-chloro-1-hydroxyethyl) phenol, phenylephrine, and eye drops” 2020, CN111378695A, filed by Enzymaster Ningbo Bio Engineering Co ltd. (Ausstehend)

    [2]   Summerer D., Kubik G., Giess M., Maurer S., “Transcription Activator-Like Effector (TALE)-based Decoding of Cytosine Nucleobases by Selective Modification Response” 2016, EP3214183 A1, filed by the University of Konstanz. (Erteilt)

    [1]   Summerer D., Kubik G., Schmidt M.J., “Direct, programmable detection of epigenetic cytosine modifications using TAL effectors” 2014, PCT/EP2014/001753, filed by the University of Konstanz. (Erteilt)

    Other

    [2]   Schiffels J., Kubik G., Dick M., „Synthetische Biologie: Mikroben für Cannabis‐Wirkstoffe“, Nachrichten aus der Chemie 2021, 69, 26-29.

    [1]   Kubik G., Chen H., Bocola M., Bong Y.K., Daußmann T., „Sustainable biocatalytic synthesis of β-hydroxy-α-amino acids on an industrial scale “, PharmaChem 2019, 5/6, 2-4.