The innate immune system has great influence on the pathogenesis or the course of diseases such as allergies, infections, tumors, or autoimmune diseases. Central regulators of the innate immune system are various classes of immune receptors. Using whole-cell biosensor assays, we identify novel immunomodulatory molecules that are potential drug candidates for the treatment of immunological diseases.
JRHDD – Joint Research Hub for Drug Discovery and Delivery
The central objective of the JRHDD project was to exploit mechanisms of innate immunity in combination with targeted drug delivery for therapy of infections as well as autoimmune and inflammatory diseases. Targeting these compounds directly to the site of infection or inflammation will support the healing process significantly. The JRHDD is continued as FPC_DD@HUJI from October 2018.
Duration: July 2017 – September 2018